What inspires me about bioinformatics is knowing that my work is leading to improvements in medical care. I am currently a senior scientist / project leader in the Computational Genomics Lab at the UC Santa Cruz Genomics Institute. In this role, I manage collaborations that involve aggregating and applying genomics data for assessing genetic risk of cancer and for developing precision medicine approaches to cancer treatment.
Scientific
? Bioinformatics scientist with more than fourteen years of post-graduate experience.
? Experienced in cancer genomics data analysis, including mutation calling, copy number estimation, RNAseq expression analysis and protein activity estimation.
? Solid knowledge of machine learning and statistical methods for sequence analysis.
? Advanced knowledge in transcriptomics and alternative splicing, including expression-based detection methods and analysis of regulatory signals.
Technical
? Computational skills including Python, Perl, R, MySQL, C/C++ and Unix/Linux.
? Bioinformatics platforms including Galaxy, Cytoscape, Bioconductor
- Genomics databases including UCSC Genome Browser, UCSC Cancer Genomics Browser, UCSC CGHub, TCGA Firehose, GenBank, ENSEMBL.
Communications
* Published over 45 peer-reviewed papers. First author of 11 and senior author of 1.
* Accomplished grant writer with a successful track record at bringing in funding.
Scientific Consortia
? Current: BRCA Challenge
? Past: TCGA Pan-Cancer Analysis Network, The Cancer Genome Atlas (TCGA), TCGA Sequencing working group, TCGA Uterine Carcinosarcoma working group, ENCODE and Mouse ENCODE consortia, Cytoscape consortium.