Past several years I have worked in developing nanopore-based sequencing techniques using nanotechnology tools. I took active part in the DNA transistor project which was one of the top 10 world changing ideas selected by Scientific American in 2010. Worked on many aspects of nanopores ranging from developing novel wetting methods, functionalization and stabilization, surface charge measurements, noise measurement and characterization, device characterization and so on. Also made a number of inventions that have been filed as patent applications or granted patents. Recently I have also worked on sensing DNA bases by tunneling using gap junction devices.
I have also proposed a novel DNA trapping method that has been published in Europhysics Letters quite recently and another instrumentation paper will appear in Review of Scientific Instruments. I continue to publish my results from a number of nanopore and DNA sensing studies.
Over the last year, I have been using machine learning techniques and also developing expertise in computational biology and bioinformatics.
As part of my current work, I provide support to IBM System Z servers to host the Rheumatoid-Arthritis challenge participants that is on-going and other new computational biology challenges like Gene Essentiality challenge hosted by Sage in collaboration with DREAM and other partners.
Yorktown Heights, NY
Research Staff Member
High performance computing, Computational biology, Nanobiotechnology and DNA Sequencing