I am director of bioinformatics at Massachusetts General Hospital and associated scientist at the Broad Institute of MIT and Harvard with over 14 year research experience in various areas of biomedicine. Current work focuses on computational and statistical analyses of next generation sequencing data from human samples and model animals to understand the relationships between genomic changes and phenotype in the context of neuro-degenerative and neuro-developmental disorders. Prior, I was a postdoctoral fellow at the Department of Molecular and Human Genetics at Baylor College of Medicine, where I worked on the problems regarding protein function-structure relationships and chromatin function. I earned my Ph.D. in theoretical physics from Texas A&M University and pursued my initial research endeavors in computational and physical chemistry at the University of Minnesota and Argonne National Laboratory.
Specialties: Computational biology, bioinformatics, functional genomics, neurogenetics, next-generation sequencing analysis, comparative protein sequence and structure analysis, protein sequence-structure-function relationships.