My interests span the computational as well as the medical and life sciences fields. From the informatics and engineering point, I worked on data mining and classification algorithms, reverse engineering of gene networks, HMM models, motif prediction algorithms, and other machine learning techniques.
In the bioinformatics application side, I worked on: applications of the Bioinformatics methods and techniques to study viral evolution, progression stages, RNA motifs and secondary structures, protein 3D structure and domain prediction, prognosis drug resistance mechanisms and modeling, modeling viral immune system networks of interactions, rational drug design, small molecule inhibitors, and siRNA design as therapeutic agents for Hepatitis C virus, and Influenza. I have many national and international collaborations with research groups in Italy, Germany, AUC, TBRI, ITI, VacSera, Kasr el-Aini and NRC in interdisciplinary research involving IT, biomedical engineering, biomedical technology, computer-aided drug design and pharmaceuticals, and medicine, through use of advanced bioinformatics techniques and technologies.
In bioinformatics supervisions, I have currently two PhD students in engineering and computer science, in addition to five MSc students in biophysics, engineering, and pharmacology.
Objectives:
? Working in a high quality academic institute in reasearch and teaching.
? Focusing on drug discovery for Hepatits C virus, Influenza and different cancers.
? Using Machine learning approaches in drug discovery, bioinformatics and systems biology.