[DrugThatGene](http://drugthatgene.pinellolab.org/) is another searchable database which provides "integrative analysis to identify druggable genes, pathways, and protein complexes from CRISPR screens".
For example, for NF1, it identifies
* 62 pathways
* 29 drug interactions
* 14 ExAC LoFs (whatever?)
* 6.22 ExAC Missense z's
* 1 ExAC pLI
and it produces this beautiful Interaction Map (which I don't know how to read, but hope to by this weekend):
${imageLink?synapseId=syn20734758&align=None&scale=100&responsive=true&altText=}
It produces downloadable CSV files for Gene, Pathway and Complex analysis, which I quote here, please feel free to customize the queries:
#### Gene Analysis
${synapsetable?query=select %2A from syn20734773&showquery=true}
#### Pathway Analysis
${synapsetable?query=select %2A from syn20734786&showquery=true}
#### Complex Analysis
${synapsetable?query=select %2A from syn20734780&showquery=true}