Dear Participants, we are pleased to announce that Nature Biotechnology supports the submission of an overview paper describing the " DREAM Single Cell Signaling in Breast Cancer Challenge" and broadly applicable insights that emerge from it. Publication in Nature Biotechnology will be contingent on a standard evaluation process including editorial assessment and peer review. Challenge participants' authorship in the resulting paper follows the guidelines given in the DREAM Principles. Good luck for the next submission and please keep in mind that Round 2 ends on the 30th October. bests Challenge organisers