phase: II grants: R01MH110928 tissue: dorsolateral prefrontal cortex methods: syn22034495 syn18425480 species: Human dataTypes: Genomic Variants Gene Expression studyType: Individual studyDescription: The BrainVar study is using RNA sequencing and whole-genome sequencing to characterize time courses of gene expression levels in postmortem human brain samples spanning developmental stages and to identify genetic variants linked with changes in expression. The goal is to gain insight into atypical trajectories of brain maturation implicated in neuropsychiatric disease. nucleicAcidSource: bulk cell numberOfIndividuals: 204 contributingInstitution: University of California, San Francisco Yale University syn21905715