Somatic Mosaicism in the brain of Tourette syndrome

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Created By Kenneth Daily kdaily

title: Somatic Mosaicism in the brain of Tourette syndrome
abstract: Somatic mosaicism arising in brain cells could explain the failure to discover consistent, replicable genetic risk factors in neuropsychiatric disorders like TS. To test the hypothesis that somatic mutations might underlie the emergence of TS, in this proposal wel discover and quantify somatic genome variation in TS and normal control brains, followed by exploration of potential functional consequences of this variation.
grantNumber: U01MH106876
institution: Yale University
institutions: Yale University
projectTitle: Somatic Mosaicism in the brain of Tourette syndrome
ndaCollection: [2961](https://nda.nih.gov/edit_collection.html?id=2961)
primaryInvestigator: Flora Vaccarino, Alexej Abyzov, Alexander Urban
primaryInvestigators: Flora Vaccarino Alexej Abyzov Alexander Urban

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