title: 3/3-Schizophrenia Genetics and Brain Somatic Mosaicism abstract: Multiple lines of evidence suggest a strong genetic component to SCZD. But, genetic variants account for only a small percentage of disease incidence suggesting that risk alleles my not be inherited through the germline, but arise through somatic mutations within neurons of affected individuals combined with a propensity for somatic mosaicism to be inherited in patients with SCZD. In this collaborative UO1 we use a variety of approaches to study somatic mosaicism in SCZD. grantNumber: U01MH106882 institution: Salk Institute for Biological Studies institutions: Salk Institute for Biological Studies projectTitle: 3/3-Schizophrenia Genetics and Brain Somatic Mosaicism ndaCollection: [2963]( https://nda.nih.gov/edit_collection.html?id=2963) primaryInvestigator: Fred Gage primaryInvestigators: Fred Gage
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