DOI: 10.1126/scitranslmed.aat6912 year: 2019 study: BrainGVEX Capstone Collection title: The DGCR5 long noncoding RNA may regulate expression of several schizophrenia-related genes. grants: U01MH103340 R01MH110920 U01MH103340 P50MH106934 UO1MH103339 U01MH103346 R21MH103877 U01MH103392 U01MH103392 U01MH103365 R01MH094714 U01MH103339 authors: Meng Q, Wang K, Brunetti T, Xia Y, Jiao C, Dai R, Fitzgerald D, Thomas A, Jay L, Eckart H, Grennan K, Imamura-Kawasawa Y, Li M, Sestan N, White KP, Chen C, Liu C journal: Science translational medicine abstract: A number of studies indicate that rare copy number variations (CNVs) contribute to the risk of schizophrenia (SCZ). Most of these studies have focused on protein-coding genes residing in the CNVs. Here, we investigated long noncoding RNAs (lncRNAs) within 10 SCZ risk-associated CNV deletion regions (CNV-lncRNAs) and examined their potential contribution to SCZ risk. We used RNA sequencing transcriptome data derived from postmortem brain tissue from control individuals without psychiatric disease pubmedId: 30545965 entity_name: Meng Science translational medicine 2019 (Pubmed ID 30545965)
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