DOI: 10.1126/scitranslmed.aat8178 year: 2019 study: BrainGVEX title: The transcription factor POU3F2 regulates a gene coexpression network in brain tissue from patients with psychiatric disorders. grants: U01MH103340 authors: Chen C, Meng Q, Xia Y, Ding C, Wang L, Dai R, Cheng L, Gunaratne P, Gibbs RA, Min S, Coarfa C, Reid JG, Zhang C, Jiao C, Jiang Y, Giase G, Thomas A, Fitzgerald D, Brunetti T, Shieh A, Xia C, Wang Y, Wang Y, Badner JA, Gershon ES, White KP, Liu C journal: Science translational medicine abstract: Schizophrenia and bipolar disorder are complex psychiatric diseases with risks contributed by multiple genes. Dysregulation of gene expression has been implicated in these disorders, but little is known about such dysregulation in the human brain. We analyzed three transcriptome datasets from 394 postmortem brain tissue samples from patients with schizophrenia or bipolar disorder or from healthy control individuals without a known history of psychiatric disease. We built genome-wide coexpression pubmedId: 30545964 entity_name: Chen Science translational medicine 2019 (Pubmed ID 30545964)
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