DOI: 10.1038/s41593-019-0463-7 year: 2019 study: CMC title: Global landscape and genetic regulation of RNA editing in cortical samples from individuals with schizophrenia. grants: U01MH116442 R01MH110921 R01MH109677 authors: Breen MS, Dobbyn A, Li Q, Roussos P, Hoffman GE, Stahl E, Chess A, Sklar P, Li JB, Devlin B, Buxbaum JD journal: Nature neuroscience abstract: RNA editing critically regulates neurodevelopment and normal neuronal function. The global landscape of RNA editing was surveyed across 364 schizophrenia cases and 383 control postmortem brain samples from the CommonMind Consortium, comprising two regions: dorsolateral prefrontal cortex and anterior cingulate cortex. In schizophrenia, RNA editing sites in genes encoding AMPA-type glutamate receptors and postsynaptic density proteins were less edited, whereas those encoding translation initiation pubmedId: 31455887 entity_name: Breen Nature neuroscience 2019 (Pubmed ID 31455887)
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