title: Panel of Normals (PON) mask project: [Brain Somatic Mosaicism Network Reference Tissue Project](/Explore/Projects/DetailsPage?id=syn21645003) toolLink: [Synapse](https://www.synapse.org/#!Synapse:syn22024535) contributor: Alexej Abyzov syn21645003: [Synapse](https://www.synapse.org/#!Synapse:syn22024535) institutions: Mayo Clinic Rochester projectTitle: Brain Somatic Mosaicism Network Reference Tissue Project toolDescription: This is a Panel of Normals (PON) mask generated using the 2504 samples from the 1000 Genomes Project whole genome sequencing at 30X coverage using the GRCh38 reference genome. For each base mask defines noisy nucleotide: A for A, C for C, G for G, T for T, R for A/G; Y for C/T, S for G/C, W for A/T, K for G/T, M for A/C, B for C/G/T, D for A/G/T, H for A/C/T, V for A/C/G