Hello, Could you please provide some methods for how information in the following two columns of the VCFs was generated? 'LOF' 'FILTER_PASS' Many thanks in advance for your help!

Created by Djuna von Maydell djuna
Hi Djuna, The best person to contact for your question is Dr. Erming Wang at the Icahn School of Medicine at Mount Sinai. Best regards, Victor
Hi Victor, Thanks very much for your quick reply. Unfortunately, I don't see a description of those two columns in the information you linked. If you could loop in the data contributor, that would be great! Many thanks, Djuna
Hi Djuna, Please refer to the [Genomic Variants (Whole Genome Sequencing) subsection](https://adknowledgeportal.synapse.org/Explore/Studies/DetailsPage/StudyDetails?Study=syn3219045#Methods-GenomicVariantsWholeGenomeSequencing) of the ROSMAP study's Methods section. For further clarity, also refer to the [ROSMAP clinical codebook](https://www.synapse.org/#!Synapse:syn3191090). If neither of these answer your question, please let me know, and I will get you in contact with the data contributor. Thank you, Victor

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