Hello, I am currently using the Mayo-RNAseq dataset and was wondering if there are certain covariates missing in the metadata file (syn23277389). The original publication (Allen et al. 2016) stated that they collected plaque and CERAD data for the subjects but those seem to be missing in the metadata file. Is there a way to obtain these covarites?

Created by Harrshavasan Congivaram HarrshaCongivaram
Hello - in the referred to publication, CERAD neuritic and cortical plaque densities are used as a means of identifying qualifying Control and Pathologic aging samples . Braak stage and Thal phase have been provided as the more broadly available neuropathological variables for this dataset.
Hi there, the MayoRNAseq metadata has Braak scores and Thal amyloid phase data, but no CERAD scores. I'm not sure about the discrepancy between our metadata and the publication -- perhaps @mxa24 could shed some light on this? As for as I know we've never had CERAD data for the Mayo study.

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