phase: I grants: R01MH094714 tissue: medial prefrontal cortex dorsolateral prefrontal cortex superior temporal gyrus cerebellum methods: syn4587616 syn8263588 syn4587615 syn17096935 species: Human dataTypes: Gene Expression Chromatin Activity diagnosis: Autism Spectrum Disorder studyType: Individual studyDescription: The UCLA-ASD study is characterizing the human brain transcriptome across multiple levels of organization – gene expression, transcript isoform, and local splicing – and relating these data to epigenetic regulatory mechanisms involving DNA methylation, histone acetylation, and microRNA expression in postmortem brain specimens from individuals with autism spectrum disorder( ASD) and neurotypical controls. nucleicAcidSource: bulk cell numberOfIndividuals: 130 contributingInstitution: University of California, Los Angeles syn5613797 syn18898607