MouseHAL

syn4590850

Created By Mette Peters Mette

phase: I
grants: R01MH105472
tissue: striatum
methods: syn5584630
species: Mouse
dataTypes: Chromatin Activity
studyType: Individual
studyDescription: The MouseHAL study is assessing whether differential gene expression in mouse striatum subsequent to haloperidol treatment (a drug used to treat schizophrenia) is related to changes in chromatin accessibility. Chromatin accessibility is one of the regulatory genomic elements thought to play an important role in gene expression. The data will provide insight into how variation in non-coding regulatory factors in the brain contributes to schizophrenia pathogenesis.
nucleicAcidSource: bulk nuclei
contributingInstitution: Duke University
syn5613808

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