Hi, I followed the instruction in _https://www.synapse.org/#!Synapse:syn21048999/wiki/607070 _ all statements were set until this for loop, that I got the permission denied. for syn_id in query_IDs: ent = syn.get(syn_id, downloadFile=False) client.download_file(ent._file_handle['bucketName'], ent._file_handle['key'], ent.name) ====================== ERROR I captured from screen ====================== self._fileobj = self._open_function(self._filename, self._mode) File "/home/ubuntu/.local/lib/python3.6/site-packages/s3transfer/utils.py", line 261, in open return open(filename, mode) PermissionError: [Errno 13] Permission denied: 'TESLA_90_1.fastq.gz.fBB22467' 1) Please kindly suggest what could be the causes of the above error. 2) If I didn't use rememberMe = True as the parameter of the login(), when I got the error and the python session terminated, do I need to wait for the new credential to be usable in the next 12 hours? 3) I could run the code above last night but got error due to the too small disk on EC2. So, the process was terminated before completed. Since then, I always got the permission denied error. Many thanks!!.