Id: bfa7544a-7ff2-4363-8d69-681753a12ace eTag: 96214912-f712-416c-b0e0-9dcfbd60c83a EntityId: syn52328044 PubmedId: 36328835 entityId: syn52328044 Component: PublicationView PubmedUrl: http://pubmed.ncbi.nlm.nih.gov/25050971/ primary_key: PublicationView_id PublicationDoi: 10.1016/j.tcb.2022.09.009 PublicationYear: 2023 PublicationAssay: 3D Cell Culture PublicationTitle: Plasticity of cancer invasion and energy metabolism PublicationTissue: Not Applicable PublicationViewId: 36328835 PublicationAuthors: Maria Parlani, Carolina Jorgez, Peter Friedl PublicationJournal: Trends Cell Biol PublicationAbstract: Energy deprivation is a frequent adverse event in tumors that is caused by mutations, malperfusion, hypoxia, and nutrition deficit. The resulting bioenergetic stress leads to signaling and metabolic adaptation responses in tumor cells, secures survival, and adjusts migration activity. The kinetic responses of cancer cells to energy deficit were recently identified, including a switch of invasive cancer cells to energy-conservative amoeboid migration and an enhanced ca[truncatedByDataCuratorApp] PublicationKeywords: Metabolic Stress, Cellular Bioenergetics, Amoeboid Migration, Migration Plasticity PublicationThemeName: Microenvironment, Method/Assay Development, Metabolism, Metastasis PublicationTumorType: Pan-cancer PublicationGrantNumber: CA210184 PublicationDatasetAlias: PublicationAccessibility: Open Access PublicationConsortiumName: PS-ON, MetNet
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