phase: I grants: R01MH105472 tissue: dorsolateral prefrontal cortex methods: syn5584622 species: Human dataTypes: Chromatin Activity diagnosis: Schizophrenia studyType: Individual studyDescription: To investigate how non-coding genetic variation contributes to schizophrenia, the HumanFC study is evaluating chromatin accessibility in frontal cortex samples from individuals diagnosed with schizophrenia and neurotypical controls. Chromatin accessibility data are compared to gene expression data generated independently in the same dorsolateral prefrontal cortex tissue aliquots. nucleicAcidSource: bulk cell numberOfIndividuals: 288 contributingInstitution: Duke University syn5613801