ipn02.8 and ipn97.4 immortalized Schwann cell lines - survival

syn53974924

Created By NF Service nf-osi-service

assay: cell viability assay
dataType: drugScreen
contentType: dataset
description: Treat ipn02.8 and ipn97.4 immortalized Schwann cell lines that have control or knocked-down levels NF1 of RASL11A expression with selective pathway inhibitors (experiments in triplicate) Selumetinib (to block ERK MAP kinase signaling) Rapamycin (to block mTOR signaling). These experiments will be performed with the pathway inhibitors used separately and in combination in comparison to vehicle control (DMSO)
progressReportNumber: 7

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