Advantages of using BAM vs. bigWig for DNase features?

Hi, I was wondering if anyone has any biological hypotheses or empirical evidence supporting that using per-base cuts (derived from BAMs) is more predictive than using the per-base fold enrichment (taken from the bigWig tracks). Are the two metrics fundamentally different? Thanks, Rajiv

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Hi, I was wondering if anyone has any biological hypotheses or empirical evidence supporting that using per-base cuts (derived from BAMs) is more predictive than using the per-base fold enrichment (taken from the bigWig tracks). Are the two metrics fundamentally different? Thanks, Rajiv

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