Hi Synapse team!
First of all, thank you for the great work you do for the scientific community.
I was exploring the clinical panels used in GENIE v16 project. I was specifically interested in the **WAKE panels** (e.g WAKE-CLINICAL-T5A, WAKE-CLINICAL-CF3 and WAKE-CA-01). Therefore, I downloaded the **genomic_information.txt** to look for the regions targeted by these panels, but I saw that the **regions covered were just of 1bp size**. However, when looking at the AACR Project GENIE 16.0-public Data Guide file, I saw that these WAKE panels cover** coding exon regions and not hotspots**. Hence, I expected to have regions much bigger than 1bp for each of the genes targeted in these panels (like it is the case for NKI or VHIO panels that also cover coding exons). Am I correct in assuming that the regions in these panels should be of bigger sizes? If so, is there a way I can get this information (ideally in a bed-like format)?
Furthermore, for some of these WAKE panels I see that in the ID column from the **genomic_information.txt** file there are more genes compared to the number of genes reported in the **assay_information.txt** file. For example, looking at WAKE-CLINICAL-CF3, in the assay_information.txt file there are just 11 genes targeted in the number_of_genes column, but when looking at the ID column from the genomic_information.txt I find 39 unique genes. Could you help me understand this discrepancy, please?
Thank you very much in advance.
Best,
Diego.