Hello,
When querying genes on cbioportal, the website categorizes each genetic alteration as
Inframe Mutation (putative driver)
Missense Mutation (putative driver)
Missense Mutation (unknown significance)
Truncating Mutation (putative driver)
Truncating Mutation (unknown significance)
Fusion
Amplification
Deep Deletion
No alterations
We want to screen out the samples with unknown significance while retaining the putative drivers, so I was how this categorization was done and whether it's part of the GENIE data set because I am having a lot of trouble finding it. The only related information I've found was the "CLIN_SIG" column in data_mutations_extended that marks each mutation as pathogenic, non pathogenic, not_provided, likely_benign, risk_factor, and uncertain_significance.
Thank you!
Created by lveoli Hello,
Have found a solution for this matter?
We are trying to find where the information the status of a mutation (driver, putative driver ...). But, we didn't manage to find it.
Thanks
Olivier
Hello,
Apologies for the delay in response. I am unsure this is something GENIE provides.
Best,
Tom
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